In short. The prevention claim, examined: what it means, what the evidence actually covers, and why a face with no line visible at rest has nothing to soften yet.

Key points

  • Ask what specifically is being prevented, how that is measured, and what the evidence for it is.
  • If the answer is that faces look better when treatment starts early, that is an opinion about appearance rather than a demonstration of prevention.

The argument for starting injections in your twenties is always the same: begin before the line appears and you will never have it. It rests on a claim much weaker than the way it is usually presented. This guide separates what is established from what is being sold.

What the treatment actually does

Treatment that relaxes the muscles of facial expression softens the lines those muscles crease into the skin. That much is well established, and in a face with a visible line it is a real and often satisfying effect. The effect is temporary: movement returns as it wears off, and the line returns with it.

Why a face with nothing visible is a poor candidate

A line seen only when you move is made by muscle, and it is normal. A line visible when the face is at rest has usually become etched into the skin, and relaxing the muscle softens only part of it. A face in its twenties with no line at rest therefore has nothing for the treatment to act on in the way the prevention claim requires. It can still be given; there is simply no problem for it to solve.

What the evidence covers, and what it does not

Evidence supports treating visible dynamic lines. It does not support the stronger claim that years of early treatment prevents lines from forming, or that people who start early need substantially less treatment later. A clinician who says the long-term benefit is unproven is not being timid; that is the accurate position.

The commitment nobody mentions at the point of sale

Starting is easy and stopping is easy, but the middle is not. Treatment in this pattern is repeated several times a year for as long as you want the effect, and the effect is the absence of something you could not see to begin with. That is a standing commitment of time and money taken on years before there is anything to treat. If you would not keep it up, starting has bought you nothing.

Prevention is a claim, not a finding

Ask what specifically is being prevented, how that is measured, and what the evidence for it is. If the answer is that faces look better when treatment starts early, that is an opinion about appearance rather than a demonstration of prevention.

Reasons to be cautious about treatment at this age

  • A face with no line visible at rest, where the stated aim is prevention rather than correction.
  • A plan presented as permanent or as something you will need less of later, without long-term evidence offered.
  • Pressure to commit to a standing schedule at the first appointment, before any assessment.

None of this makes the treatment unreasonable for someone who has a visible line and wants it softened. It makes the prevention argument, at this age, something to interrogate rather than accept, and the honest answer for most faces in their twenties is that there is nothing here yet worth a standing commitment.

Related reading

Frequently asked questions

If I start now, will I need less treatment later?

That is the claim, and it is made more confidently than the evidence supports. What is well established is that treating a line made by muscle softens that line while the effect lasts. Extending that into a claim about needing less treatment decades later requires evidence that repeated treatment changes the long-term course, and that evidence is not what the marketing implies.

What happens if I start and then stop?

The effect wears off over months and the movement returns. Nothing is permanently changed by having had treatment, and skin does not become dependent on it in any meaningful sense. What does persist is the habit and the calendar: stopping is easy in principle and harder once a rhythm and an annual spend have been established.

Is there a harm in starting early even if it does not prevent anything?

There is a cost rather than a harm. You spend years and a considerable amount of money treating movement that nobody can see, and you accept the small risks of the procedure — bruising, asymmetry, an uncommon reaction — repeatedly during a period when there was nothing to treat. That is a poor trade rather than a dangerous one, and it is worth naming as such.

Risks & Limitations

  • Nothing offered at this age is risk-free; every treatment has a complication rate.
  • Treated skin can leave a pigment mark of its own, and deeper skin tones carry the higher risk.
  • Acne scarring is the one outcome in this decade that cannot be reversed once it has formed.
  • Over-treating the barrier turns manageable skin into reactive skin, and recovery takes months.

When to Seek Care

  • Acne that is deep, painful or leaving marks — see a doctor rather than a counter assistant.
  • A mole or mark that changes size, shape or colour, or that bleeds.
  • Sudden hair loss, or a rash after starting a new medicine.
  • A reaction to a product bought online, especially swelling, redness or rebound breakouts.

References & Further Reading

  • American Society of Plastic Surgeons (ASPS) — procedure and safety guidance
  • National Institute for Health and Care Excellence (NICE, UK) — relevant guidance
  • Cochrane Library — systematic reviews
  • Chinese Medical Association Plastic Surgery Branch — clinical guidance

Medically reviewed by Tongchun Mao, MD (毛彤春), Deputy Director & Head of Aesthetic Surgery. Last reviewed: 19 September 2026.

This page is patient education, not medical advice, and it does not cite individual studies. Discuss your own case with a qualified clinician. To arrange an assessment at Chongqing West District Hospital, see Contact & Consultation.